The Plasma membrane in health and disease

质膜在健康和疾病中的作用

• 批准号: nhmrc : GNT1037320
• 负责人: Prof Alpha Yap
• 金额: $ 473.47万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Programs
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/plasma-membrane-health-disease/1344353
• 关键词: Plasma; membrane; health; disease

This research program aims to gain a detailed understanding of the organisation of the cell surface at the molecular level. The cell surface is organised into domains with distinct functions. Visualisation of these domains, identifying their important components, and understanding how they form and function will have huge importance for therapeutic strategies aimed at combatting the changes associated with cell transformation in cancer and in other human diseases such as muscular dystrophy.

该研究计划旨在从分子水平上详细了解细胞表面的组织。细胞表面被组织成具有不同功能的结构域。这些领域的可视化，识别它们的重要组成部分，并了解它们的形成和功能，对于旨在对抗癌症和其他人类疾病（如肌营养不良症）中与细胞转化相关的变化的治疗策略具有巨大的重要性。