BIOPHYSICAL INSTRUMENTATION AND METHODOLOGY

该项目旨在开发新的仪器和方法， 改进现有的仪器和技术， 生物大分子的表征及其研究 交互. 分析超浓缩，技术辅助 以及使用数学建模的数据分析方法 适用于这些技术的是感兴趣的主要领域。 研究继续应用数学建模， 超离心分析的问题，以及新的 进行实验和分析数据的方法。 特别是， 蛋白质-核酸分析的重大突破， 通过设计一种新的方法， 进行实验和分析数据。

The project is intended to develop new instrumentation and methods, and to improve existing instrumentation and techniques, for the characterization of biological macromolecules and the study of their interactions. Analytical ultracentrifugation, the techniques ancillary to it, and methods of data analysis using mathematical modeling appropriate for these techniques are the major areas of interest. Studies have continued on the application of mathematical modeling to problems of ultracentrifugal analysis, and on the development of new methods of performing experiments and analyzing data. In particular, a major breathrough in the analysis of protein-nucleic acid and protein-protein interactions has been achieved by devising a new method of performing experiments and analyzing data.