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中文摘要
翻译
显微镜和图像分析实验室(MIL)是密歇根大学综合癌症中心(UMCCC)的形态学核心。MIL成立于1977年,是一个大学范围内共享的用户显微镜和成像设施,并于1995年成为UMCCC核心设施。所有仪器都由研究人员共享,用于细胞和组织形态学及超微结构的研究。MIL由密歇根大学医学院细胞与发育生物学系管理。Morphology Core为UMCCC研究人员提供了一种具有成本效益的机制,使他们能够使用最先进的成像仪器,而这些仪器由于高昂的购置和维护成本而无法在单个实验室中使用。获得训练有素的人员与多年的专业知识也提供了形态核心,并提供给所有UMCCC成员和他们的工作人员。MIL由一名全职经理、一名实验室主管、五名研究助理和仪器分析师组成。常规组织学和电子显微镜样品处理,切片,染色和分析可与事先咨询和安排。重点是培训研究者或其指定的工作人员,以根据需要正确操作每台设备,以满足其成像研究需求。
英文摘要
The Microscopy and Image-analysis Laboratory (MIL) serves as the Morphology Core for the University of Michigan Comprehensive Cancer Center (UMCCC). The MIL was established in 1977 as a University wide shared user microscopy and imaging facility and became a UMCCC Core Facility in 1995. All instrumentation is used on a shared basis by investigators for studies of cell and tissue morphology and ultrastructure. The MIL Is housed and administered within the Department of Cell & Developmental Biology at the University of Michigan Medical School. The Morphology Core offers a cost-effective mechanism for UMCCC researchers to have access to state-of-the-art imaging instrumentation that would not otherwise be available in Individual laboratories because of high acquisition and maintenance costs. Access to highly trained personnel with many years of expertise is also provided by the Morphology Core and is available to all UMCCC members and their staff. The MIL is staffed by a full time manager, a laboratory supervisor, five research associates, and Instrument analyst. Routine histology and electron microscopy sample processing, sectioning, staining, and analysis is available with prior consultation and scheduling. Emphasis Is placed on training the research investigator or their designated staff to properly operate each piece of equipment as needed to meet their imaging research needs.
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Targeting breast cancer stem cells
Targeting breast cancer stem cells
Targeting breast cancer stem cells
Cancer Cell Biology
国内基金
海外基金
分化肌细胞脱细胞ECM-cells sheet 3D 支架构建及其促进容积性肌组织缺损再 生修复应用及机制研究
CAFs-TAMs-tumor cells调控在HRHPV感染致癌中的作用机制研究及AI可追溯预测模型建立
  • 批准号:
    82072862
  • 项目类别:
    面上项目
  • 资助金额:
    56.0万元
  • 批准年份:
    2020
  • 负责人:
    徐云升
  • 依托单位:
S100A8/A9--Myeloid cells特异性可溶性表氧化物水解酶(sEH)基因敲除改善胰岛素抵抗的新靶点
  • 批准号:
    82070825
  • 项目类别:
    面上项目
  • 资助金额:
    53.0万元
  • 批准年份:
    2020
  • 负责人:
    徐西振
  • 依托单位:
Leader cells通过CCL5调控糖酵解及基质硬度促进结直肠癌集体侵袭的 作用机制
  • 批准号:
    81903002
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.5万元
  • 批准年份:
    2019
  • 负责人:
    王斐斐
  • 依托单位: