Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis Patients

我们扩大了我们的工作，将真菌作为健康成年人多个皮肤部位的人类皮肤微生物组的一部分，并继续调查皮肤微生物组波动与皮肤疾病的相关性。2013财年，我们完成了关于真菌皮肤微生物群健康成年人的分析并发表了一篇手稿。我们继续研究原发免疫缺陷皮炎(高IgE综合征和Wiskott-Aldrich综合征)患者的皮肤微生物组，以及先前登记的受试者的后续抽样访问。该项目的测序由美国国立卫生研究院路线图项目--人类微生物组项目--资助。我们一直在继续分析上一财年特应性皮炎、高IgE综合征和Wiskott-Aldrich综合征患者的微生物组数据。

We have expanded our work by including studies of fungi as part of the human skin microbiome of multiple skin sites in healthy adults as well as continued to investigate the relevance of the skin microbiome fluctuations to skin diseases. In fiscal year 2013, we completed analysis and published a manuscript about the fungal skin microbiome healthy adults. We continue to study the skin microbiome in patients primary immunodeficiencies with dermatitis (hyper-IgE syndrome and Wiskott-Aldrich syndrome), in addition to follow-up sampling visits from previously enrolled subjects. The sequencing for this project is funded by the National Institutes of Health Roadmap Project, The Human Microbiome Project. We have been continuing to analyze the microbiome data from patients with atopic dermatitis, hyper-IgE syndrome and Wiskott-Aldrich syndrome in the last fiscal year.