IMPORTANCE OF PATERNAL CARE

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：确定灵长类动物良好父母教养的促进者。 与人类一样，合作繁殖的绒猴和罗望子显示出相当大的父亲指导婴儿照顾的能力。然而，绒猴和金丝猴的父亲比母亲花在照顾婴儿上的时间更多。父亲在分娩前表现出荷尔蒙的变化，这有助于婴儿的反应。我们发现，经验丰富的父亲猴对婴儿有高度但不同的反应。接受婴儿反应测试的男性对活着的婴儿或婴儿发出的声音做出反应的积极性很高。我们发现，催乳素降低的男性对婴儿暗示的反应也较低，而在婴儿出生前睾酮水平最高的男性也对婴儿暗示表现出最大的反应。此外，因果关系研究表明，催乳素有助于调节绒猴和金丝猴的体重。降低催乳素与父亲在婴儿期减掉大量体重有关，而增加催乳素则通过照顾婴儿来防止体重减轻。我们认为在绒猴身上存在有利于雄性父母照顾的荷尔蒙条件。这项研究使用了WNPRC Assay Services。 在本报告所述期间之前，国立卫生研究院MIMH的资助已结束；现已出版了三份出版物。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: To determine the facilitators of good parenting in primates. As in humans, cooperative breeding marmosets and tamarins show a considerable amount of father directed infant care. However, marmoset and tamarin fathers spend more time than the mother caring for infants. Fathers before delivery show hormonal changes that facilitate infant responsiveness. We found that experienced father marmosets are highly but variably responsive to infants. Males tested for their infant responsiveness are highly motivated to respond to a live infant or to vocalizations produced by an infant. We found that males with lowered prolactin also showed lower responsiveness to infant cues while males who had the highest levels of testosterone prior to infant birth also show the most responsiveness to infant cues. Additionally causal studies indicate that prolactin helps regulate weight in marmosets and tamarin monkeys. Lowering prolactin is associate with fathers losing a significant amount of weight during the infant period while increasing prolactin prevents weight loss with infant care. We suggest that there are hormonal conditions that faciliate male parental care in the marmoset monkey. This research used WNPRC Assay Services. NIH MIMH funding ended before this reporting period; three publications have resulted.