Design of Molecular Assembly for Extraction of Biomolecules

生物分子提取的分子组装设计

基本信息

  • 批准号:
    21360383
  • 负责人:
  • 金额:
    $ 11.4万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    2009
  • 资助国家:
    日本
  • 起止时间:
    2009 至 2011
  • 项目状态:
    已结题

项目摘要

Liquid/liquid extraction is one of the useful separation techniques involving a molecular recognition event. Despite a number of studies on liquid/liquid extraction, it is still a challenge to extract a target biomolecule selectively to another phase based on the precise recognition at a liquid/liquid interface. In particular, if the target is a biomacromolecule, the presence of multifunctional groups prevents selectivity and versatility in liquid/liquid extraction. We here propose the sequence-specific liquid/liquid extraction of DNA oligonucleotides using reverse micelles with a DNA-surfactant. A reverse micelle, which is a nanoscale water pool surrounded by surfactant molecules in an organic solvent, is one of the highly useful tools for extraction of biomolecules.
液/液萃取是涉及分子识别事件的有用分离技术之一。尽管对液/液萃取进行了大量的研究,但基于液/液界面处的精确识别将目标生物分子选择性地萃取到另一相仍然是一个挑战。特别地,如果目标是生物大分子,则多官能基团的存在防止了液/液萃取中的选择性和多功能性。在这里,我们提出了序列特异性液/液萃取的DNA寡核苷酸使用反胶束与DNA表面活性剂。反胶束是一种在有机溶剂中被表面活性剂分子包围的纳米级水池,是提取生物分子的非常有用的工具之一。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Activation and stabilization of enzymes in ionic liquids
  • DOI:
    10.1039/b926130c
  • 发表时间:
    2010-01-01
  • 期刊:
  • 影响因子:
    3.2
  • 作者:
    Moniruzzaman, Muhammad;Kamiya, Noriho;Goto, Masahiro
  • 通讯作者:
    Goto, Masahiro
Design of a cytochrome P450BM3 reaction system linked by two-step cofactor regeneration catalyzed by a soluble transhydrogenase and glycerol dehydrogenase
可溶性转氢酶和甘油脱氢酶催化的两步辅因子再生连接的细胞色素P450BM3反应系统的设计
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    0
  • 作者:
    T. Mouri;T. Shimizu;N. Kamiya;H. Ichinose;M. Goto
  • 通讯作者:
    M. Goto
Biocatalysis in Water-in-Ionic Liquid Microemulsions
离子液体包水微乳液中的生物催化
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    3.9
  • 作者:
    M. Moniruzzaman;N. Kamiya;M. Goto
  • 通讯作者:
    M. Goto
Preparation of Lactose-Modified Cellulose Films by a Nonaqueous Enzymatic Reaction and their Biofunctional Characteristics as a Scaffold for Cell Culture
  • DOI:
    10.1021/bm900089j
  • 发表时间:
    2009-05-01
  • 期刊:
  • 影响因子:
    6.2
  • 作者:
    Esaki, Kei;Yokota, Shingo;Wariishi, Hiroyuki
  • 通讯作者:
    Wariishi, Hiroyuki
Transglutaminase-mediated protein labeling with a designed peptide loop
使用设计的肽环进行转谷氨酰胺酶介导的蛋白质标记
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GOTO Masahiro其他文献

Property of Prestressed Concrete Using MSW Slag
利用城市生活垃圾矿渣预应力混凝土的性能
Recovery of Cobalt and Manganese from Spent Lithium-ion Batteries using a Phosphonium-based Ionic Liquid
使用磷基离子液体从废旧锂离子电池中回收钴和锰
  • DOI:
    10.15261/serdj.28.79
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    FIRMANSYAH Mochmad L.;FAJAR Adroit T. N.;MUKTI Rino R.;ILMI Thalabul;KADJA Grandprix T. M.;GOTO Masahiro
  • 通讯作者:
    GOTO Masahiro

GOTO Masahiro的其他文献

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{{ truncateString('GOTO Masahiro', 18)}}的其他基金

Effects of cooking condition by low -temperature steaming for taste and nutrient composition of vegetables.
低温蒸煮条件对蔬菜口感和营养成分的影响
  • 批准号:
    18K02197
  • 财政年份:
    2018
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Investigation into growth mechanism of polymer nanowires synthesized by a pulsed laser irradiation
脉冲激光辐照合成聚合物纳米线生长机理的研究
  • 批准号:
    24656058
  • 财政年份:
    2012
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Design of Nano-reactor Programmed by Synthesized DNA
合成DNA编程的纳米反应器的设计
  • 批准号:
    24656472
  • 财政年份:
    2012
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Studies on the relations of physicochemical factors and the differences of taste by cooking methods using various potato cultivars.
研究不同马铃薯品种的理化因素关系和烹调方法带来的口感差异。
  • 批准号:
    24500959
  • 财政年份:
    2012
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Fatigue characteristics of ultrafine grained copper for the application to components
应用于部件的超细晶铜的疲劳特性
  • 批准号:
    23560093
  • 财政年份:
    2011
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Reaction Control of Nanoreactor by Utilizing DNA Hybridization
利用 DNA 杂交控制纳米反应器的反应
  • 批准号:
    22656179
  • 财政年份:
    2010
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Reduction of friction force by using a piezoelectric effect and development of low frictional coatings.
利用压电效应减少摩擦力并开发低摩擦涂层。
  • 批准号:
    21246030
  • 财政年份:
    2009
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Study on the application of ultrafine grained copper to electric materials.
超细晶铜在电工材料中的应用研究
  • 批准号:
    20560080
  • 财政年份:
    2008
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Novel concept for creating molecul ar assembly-assisted extraction
创建分子组装辅助提取的新概念
  • 批准号:
    19360354
  • 财政年份:
    2007
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Condition of the cooking by Cook-chill system, and the change of vitamin and taste during storage of cooking product
Cook-chill系统的烹调状况,以及烹调产品储存期间维生素和味道的变化
  • 批准号:
    19500669
  • 财政年份:
    2007
  • 资助金额:
    $ 11.4万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

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Solvent extraction simulation of radioactive elements based on computational chemical analyses
基于计算化学分析的放射性元素溶剂萃取模拟
  • 批准号:
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    2023
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通过电渗析和溶剂萃取技术回收锂
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废钕磁铁中高温溶剂萃取稀有元素
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从红甜菜 (Beta vulgaris L.) 加工废物中进行绿色溶剂萃取,然后封装富含抗氧化剂的提取物。
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水系铂族金属的溶剂萃取及铂族金属回收基本工艺的构建
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从红甜菜 (Beta vulgaris L.) 加工废物中进行绿色溶剂萃取,然后封装富含抗氧化剂的提取物。
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