Study of regulation of anti-diuretic hormone gene expression

提示张力反应性增强子结合蛋白（TonEBP）可能通过抗利尿激素精氨酸缩血管素（AVT）的调节作用参与了鸟类调节的表达。我们发现，TonEBP结合的AVT基因的上部区域的凝胶迁移率变动分析方法。此外，TonEBP的免疫反应定位观察到PVN（室旁核）和SON（视上核）与许多VT阳性细胞。提示瞬时受体电位香草酸（TRPV）参与了鸟类的呼吸调节。

We suggested that Tonicity-responsive Enhancer Binding Protein (TonEBP) participated in expression of birds adjustment by the osmoregulation of arginine vasotocin (AVT) which was antidiuretic hormone. We revealed that TonEBP bound to the upper region of the AVT gene by the gel mobility shift assay method. In addition, an immunoreactive localization of TonEBP was observed in PVN (para-ventricular nucleus) and SON (supra optic nucleus) with many VT-positive cells. It was suggested that TRPV (Transient Receptor Potential Vanilloid) participated in the osmoregulation of birds.