Study of osmoregulation in birds

鸟类渗透调节的研究

基本信息

  • 批准号:
    14360165
  • 负责人:
  • 金额:
    $ 9.47万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    2002
  • 资助国家:
    日本
  • 起止时间:
    2002 至 2004
  • 项目状态:
    已结题

项目摘要

For long time, it has been not clear about the osmoreceptor on the osmoregulation. Recently, aquaporin 4(AQP4) has been a candidate as an osmoreceptor, but there are no clear evidence about that. We cloned chicken AQP4 cDNA and determined its sequence. We analyzed the gene expression of AQP4 in the chicken hypothalamus in related with osmostimulation. AQP4 gene expression in the chicken increased by hyperosmolality. Threrefore, these results suggest that AQP4 may involve osmoreceptor in the chicken. Since there are no observations about the increase of AQP4 gene expression by hyperosmolality in the mammals, such increase is specific thing in the chicken.Comparing arginine vasotocin(AVT) gene expression between layer and broiler strain after water deprivation, both strains chick decreased body weights and increased plasma osmolality. On AVT gene expression, AVT gene expression increased in layer but not in broiler. These results suggested that there was some different mechanism of osmoregulation between two strains.It has been considered that neuropeptide Y(NPY) is a important role for feeding behavior. But, after water deprivation, NPY gene expression increased in the chicken. Therefore, these data suggest that NPY has a pivotal role on the water homeostasis in the chicken.
长期以来,关于β受体对β受体的调节作用尚不清楚。近年来,水通道蛋白4(aquaporin 4,AQP4)被认为是一种新型的神经递质受体,但目前还没有明确的证据。本研究克隆了鸡AQP4基因的cDNA并测定了其序列。本研究分析了AQP4基因在鸡下丘脑中的表达及其与神经刺激的关系。AQP4基因在高渗环境中表达增加。因此,AQP4可能与鸡的AQP4受体有关。由于在哺乳动物中没有观察到AQP4基因表达随高渗而增加的现象,因此这种增加在鸡中是特有的,比较蛋鸡和肉仔鸡品系在禁水后精氨酸催产素(AVT)基因的表达,两种品系的鸡体重均下降,血浆渗透压均升高。在AVT基因表达方面,蛋鸡AVT基因表达量增加,而肉鸡AVT基因表达量没有增加。这些结果表明,两种品系的摄食调节机制不同,神经肽Y(NPY)可能在摄食行为中起重要作用。但是,在水剥夺后,NPY基因的表达在鸡增加。因此,这些数据表明,神经肽Y在鸡体内的水平衡中具有关键作用。

项目成果

期刊论文数量(70)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Identification of Spermatogenic cells expressiong protamine mRNA in Japanese quail by RT-PCR
RT-PCR 鉴定日本鹌鹑生精细胞表达鱼精蛋白 mRNA
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Upi Chairun Nisa;Tsukada A.;Takagi S.;Yamamoto I.;Ha Y.;Hrabia A.;Saito N.;Shimada K.
  • 通讯作者:
    Shimada K.
Effect of central administration of prolactin-releasing peptide on feeding in chicks.
催乳素释放肽中枢给药对雏鸡采食的影响。
  • DOI:
  • 发表时间:
    2004
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Tachibana;T.;Saito;S.;Tomonaga;S.;Takagi;T.;Saito;E.-S.;Nakanishi;T.;Koutoku;T.;Tsukada;A.;Ohkubo;T.;Boswell;T.;Furuse;M.
  • 通讯作者:
    M.
Cloning of duck PRL cDNA and genomic DNA
  • DOI:
    10.1016/j.ygcen.2004.11.017
  • 发表时间:
    2005-03-01
  • 期刊:
  • 影响因子:
    2.7
  • 作者:
    Kansaku, N;Ohkubo, T;Shimada, K
  • 通讯作者:
    Shimada, K
Changes in mRNA expression of MMP-2 in the Mullerian duct of chicken embryo
cDNA cloning and mRNA expression of transformer 2(Tra2) in chicken embryo.
鸡胚变压器2(Tra2)的cDNA克隆及mRNA表达。
  • DOI:
  • 发表时间:
    2002
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Yamamoto I.;Tsukada A.;Saito N.;Shimada K.
  • 通讯作者:
    Shimada K.
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SAITO Noboru其他文献

Study of Mountain-Climbing Learning Method of Mathematics Education in Laos For Lower Secondary School Students
老挝初中生数学教育爬山式学习法研究
算数学習におけるふり返りとまとめ
数学学习的反思与总结
アジア諸国の科学教育改革と日本への示唆-中国(上海)、科学的素養の育成を目指して
亚洲国家的科学教育改革及对日本的启示 - 中国(上海)旨在培养科学知识
Study of the Mountain-Climbing Learning Method of Mathematics Education in Laos : For Lower Secondary School Students
老挝数学教育登山式学习法研究:初中生
日本の高等教育機関における「持続可能な開発のための教育 (ESD)」への取り組み
日本高等教育机构的可持续发展教育 (ESD) 举措
  • DOI:
  • 发表时间:
    2009
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Somphone PHASOUK;SAITO Noboru;北村友人;馬場卓也;橋本健夫・劉卿美・大高泉;佐野正彦;菅井裕行・金森光紀;歳森敦;佐野正彦;北村友人
  • 通讯作者:
    北村友人

SAITO Noboru的其他文献

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{{ truncateString('SAITO Noboru', 18)}}的其他基金

Academic Investigation Research on Strategy of Founding Graduate School of Teacher Training College to Promote Self-sustaining Improvements in Developing Country
师范院校设立研究生院促进发展中国家自我持续进步的策略学术调查研究
  • 批准号:
    15H05203
  • 财政年份:
    2015
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of Mathematics Teaching Model to Produce Mathematical Innovation and Application in Teacher Education
发展数学教学模式促进数学在教师教育中的创新与应用
  • 批准号:
    15K04457
  • 财政年份:
    2015
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Academic Investigation Research for Establishing a Graduate School of Teacher Training College in Developing Country
发展中国家设立师范学院研究生院的学术调查研究
  • 批准号:
    23252013
  • 财政年份:
    2011
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (A)
Study of regulation of anti-diuretic hormone gene expression
抗利尿激素基因表达调控的研究
  • 批准号:
    23580388
  • 财政年份:
    2011
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Academic Investigation Research for Establishing a Graduate School of University of Education in Developing Country
发展中国家设立教育大学研究生院的学术调查研究
  • 批准号:
    20402067
  • 财政年份:
    2008
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Study of Academic Investigation for Establishing Graduate School of University of Education in a Developing Country
发展中国家设立教育大学研究生院的学术考察研究
  • 批准号:
    18402044
  • 财政年份:
    2006
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
The Development of Teacher Training Core Curriculum of Mathematics in University of Education
教育学院数学师资核心课程的开发
  • 批准号:
    16500555
  • 财政年份:
    2004
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The study of molecular marker expression in evaluation for the malignancy potential of colorectal cancer
分子标志物表达在结直肠癌恶性潜能评估中的研究
  • 批准号:
    16591357
  • 财政年份:
    2004
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Osmoreceptorand arugihine vasotocin I n chicken
鸡渗透压感受器和阿鲁吉辛催产素
  • 批准号:
    12660253
  • 财政年份:
    2000
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
RELATION AMONG THE STRUCTURAL THINKING, THE CREATIVE POWER AND POWER OF EXPRESSION
结构思维、创造力和表达力之间的关系
  • 批准号:
    10680188
  • 财政年份:
    1998
  • 资助金额:
    $ 9.47万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)

相似国自然基金

鸡脂肪组织生长发育的分子遗传学基础
  • 批准号:
    30430510
  • 批准年份:
    2004
  • 资助金额:
    130.0 万元
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蛋鸡与肉鸡骨骼肌生长发育差异的分子遗传学基础
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《鸡星球》:亚洲家禽繁荣中的化学纠缠
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