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SYNTHESIS OF MORPHINE IN ANIMAL TISSUE FROM INTERMEDIATES OF PLANT BIOSYNTHESIS

SYNTHESIS OF MORPHINE IN ANIMAL TISSUE FROM INTERMEDIATES OF PLANT BIOSYNTHESIS
从植物生物合成中间体在动物组织中合成吗啡
批准号:
3964166
负责人:
A BROSSI
金额:
$0.0万
依托单位国家:
美国
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财政年份:
--
资助国家:
美国
项目状态:
未结题
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英文摘要
Rats given thebaine and (+)-salutaridine, intermediates in the biosynthesis of morphine in poppy plants, produced significant levels of codeine and morphine in tissue of rats, suggesting that they may represent intermediates in the mammalian synthesis of morphine. Since both, (+)-salutaridine and (-)-thebaine were as pure as possible, it seems justify to exclude contamination of the two alkaloids with codeine or morphine as the source of mammalian codeine.
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STUDIES REGARDING THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
STUDIES REGARDING THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE
NORTROPANE ALKALOIDS
ANALYTICAL REAGENTS FROM DIHYDROFLUORESCEIN
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