NIEHS Statistical Consulting Service

统计咨询处（SCS）于1996年正式成立，为NIEHS研究人员从实验室和人类/流行病学研究中获得的数据的设计、分析和解释提供统计和计算专业知识。统计局提供的统计专业知识范围从数据分析方面的建议到更广泛的合作研究工作，从而在主题期刊上共同发表文章。这些咨询项目涉及各种各样的科学努力，包括实验室和人体研究。生物统计处的一些统计人员在不同程度上参与了国家统计局的工作。本资源评论报告总结了生物统计处统计学家向NIEHS DIR提供的咨询/合作。

The Statistical Consulting Service (SCS) was formally established in 1996 to provide statistical and computational expertise in the design, analysis, and interpretation of data obtained from laboratory and human/epidemiological studies conducted by the researchers at NIEHS. Statistical expertise provided by the SCS ranges from advice regarding data analysis to more extensive collaborative research efforts that result in joint publications in subject matter journals. These consulting projects involve a variety of scientific endeavors, including both laboratory and human studies. A number of statisticians from the Biostatistics Branch are involved in varying degrees with the SCS. This Resource Review report summarizes the consulting/collaborations provided by the Biostatistics Branch statisticians to the NIEHS DIR. Examples of project collaborations include; (i) Effect of pre-natal exposure to HIV/AIDS drugs AZT, 3TC, and AZT+3TC on cardiac damage, in particular the mitochondrial DNA, in mice. (ii) Study of the effects of kava extract, a common dietary supplement, on cell proliferation in liver and its effects on cholesterol levels. (iii) Study of changes in gene expression of heart tissue among rats exposed to bis (2-chloroethoxy) methane (iv) Study of the effects of some antioxidant dietary supplements in mice that were genetically predisposed to prostate cancer. (v) Study of the mechanism of acrylamide carcinogenicity using genetically modified mice. (vi) Study of the effects of residential exposure to radon on lung cancer. (vii) Effect of improper uterine lining development on survival of pregnancy.