Multi-ethnic Study Of Atherosclerosis - Vision Component
Multi-ethnic Study Of Atherosclerosis - Vision Component
批准号:
9362377
负责人:
Mary Frances Cotch
金额:
$15.74万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
African AmericanAgingAir PollutionAncillary StudyAsian AmericansAtherosclerosisBiologicalCandidate Disease GeneCardiovascular DiseasesCardiovascular systemCaucasiansCohort StudiesCollaborationsCommunitiesContractsDNADataData AnalysesDepositionDiabetic RetinopathyDiseaseEpidemiologyEthnic OriginEventEyeFamilyFamily StudyFamily memberFundingFundus photographyGenesGeneticGenome ScanGenomicsGenotypeGrantHealthHispanic AmericansHispanicsImageIndividualInstitutionIntramural Research ProgramLaboratoriesLungMacular degenerationManuscriptsMeasuresMedical centerMeta-AnalysisMethodologyMicrovascular DysfunctionNational Heart, Lung, and Blood InstituteParentsParticipantPathologyPeer ReviewPhenotypePhotographyPredictive FactorPreparationPrincipal InvestigatorProtocols documentationPublicationsPublishingReadingResearchResearch PersonnelResourcesRetinalRoleSamplingSeveritiesSiblingsSystemic diseaseTestingTimeUltrasonographyVariantVisionVisitVisualVisual AcuityVisual impairmentWomanX-Ray Computed Tomographyagedbaseclinical phenotypecohortdatabase of Genotypes and Phenotypesdesigndigitalgenetic analysisgenetic associationgenetic linkage analysisgenome-widehigh riskimaging modalityindexinginternational partnershipmembermennovelpopulation basedsextrait
中文摘要
梅萨的研究正在进行中。MESA第五次考察访问始于2010年4月,于2012年初完成。参与者目前正在接受健康活动的跟踪。
对各种眼部表型的分析,包括视网膜微血管疾病,已经导致了多篇已发表的手稿,更多的手稿正在准备中。2010年8月,基因和眼部表型数据开始在DBGaP上发布。在Mesa Share、Charge和BioProject的赞助下进行的遗传分析正在进行中。
MESA有许多辅助研究,包括肺部分(由NHLBI资助)和空气污染部分(由EPA资助),使所有研究人员能够利用有限的资源获得最大的科学优势。为了整合和分析不同研究组成部分的数据而进行的讨论导致了几个多学科的合作,产生了许多同行评议的科学出版物,其中许多都是新奇的,很可能被认为风险太高,根本无法单独获得资金。
有关MESA研究及其辅助研究的更多信息,包括参与研究人员和机构的完整名单以及完整、最新的出版物名单,请访问http://www.mesa-nhlbi.org.有关如何访问MESA数据的信息,请参阅DBGaP(http://www.ncbi.nlm.nih.gov/gap).
英文摘要
The MESA study is on-going. MESA study visit five began in April 2010 and was completed in early 2012. Participants are currently being followed for health events.
Analyses of various ocular phenotypes, including retinal microvascular disease, have resulted in multiple published manuscripts with more under preparation. Genotype and ocular phenotype data began to be released on dbGaP in August 2010. Genetic analyses under the auspices of MESA SHARe, CHARGE, and the BioProject are on-going.
MESA has numerous ancillary studies, including a lung component (funded by NHLBI) and an air pollution component (funded by the EPA), allowing all investigators to leverage modest resources for maximal scientific advantage. Discussions to integrate and analyze data across various study components have resulted in several multi-disciplinary collaborations producing numerous peer-reviewed scientific publications, many of which are novel and would likely have been considered too high-risk to have ever received funding on their own.
More information about the MESA Study and its ancillary studies, including a full list of participating investigators and institutions and a complete, up-to-date list of publications, can be found at http://www.mesa-nhlbi.org. For information on how to access MESA data, refer to dbGaP (http://www.ncbi.nlm.nih.gov/gap).
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会议论文
Age-Related Macular Degeneration: A Genetic Epidemiology Study in the Amish
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批准号:8556829
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项目类别:
-
资助金额:$1.22万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Vision In Nhanes
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批准号:8737628
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项目类别:
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资助金额:$1.18万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Age, Gene/environment Susceptibility Study In Iceland - Ocular Component
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批准号:8339767
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项目类别:
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资助金额:$14.09万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Atherosclerosis Risk in Communities - Retinal component
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批准号:8339777
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项目类别:
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资助金额:$0.33万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Age, Gene/environment Susceptibility Study In Iceland - Ocular Component
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批准号:7594077
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项目类别:
-
资助金额:$15.14万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Multi-ethnic Study Of Atherosclerosis - Vision Component
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批准号:8149162
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项目类别:
-
资助金额:$15.61万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
MESA Family - Ocular Component
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批准号:7968358
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项目类别:
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资助金额:$1.53万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Multi-ethnic Study Of Atherosclerosis - Vision Component
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批准号:7968338
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项目类别:
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资助金额:$12.25万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Multi-ethnic Study Of Atherosclerosis - Vision Component
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批准号:8339769
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项目类别:
-
资助金额:$16.39万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Age, Gene/environment Susceptibility Study In Iceland - Ocular Component
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批准号:8556825
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项目类别:
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资助金额:$32.87万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Age, Gene/environment Susceptibility Study In Iceland - Ocular Component
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批准号:8938310
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项目类别:
-
资助金额:$35.64万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Age, Gene/environment Susceptibility Study In Iceland - Ocular Component
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批准号:7734620
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项目类别:
-
资助金额:$10.63万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Vision In Nhanes
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批准号:7734621
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项目类别:
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资助金额:$1.77万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
MESA Family - Ocular Component
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批准号:7734630
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项目类别:
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资助金额:$5.31万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Multi-ethnic Study Of Atherosclerosis - Vision Component
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批准号:10019991
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项目类别:
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资助金额:$16.52万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Multi-ethnic Study Of Atherosclerosis - Vision Component
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批准号:10260288
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项目类别:
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资助金额:$22.81万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Vision In Nhanes
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批准号:9362376
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项目类别:
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资助金额:$4.99万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Atherosclerosis Risk in Communities - Retinal component
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批准号:7968360
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项目类别:
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资助金额:$1.23万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Vision In Nhanes
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批准号:8556826
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项目类别:
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资助金额:$1.22万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
Age, Gene/environment Susceptibility Study In Iceland - Ocular Component
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批准号:10019989
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项目类别:
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资助金额:$31.67万
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财政年份:--
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负责人:Mary Frances Cotch
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依托单位:
海外基金