MESA Family - Ocular Component

2004年5月开始为梅萨家庭招募非裔美国人和西班牙裔同胞。 到2006年底，登记工作完成时，共有608个家庭的3 026艘船舶登记。 在这个梅萨家族样本上，候选基因的表型注释和基因分型已经完成。 候选基因分析的初步结果表明，以前需要进一步进行基因分型，这项活动一直在进行中。 对梅萨指数病例子样本（来自原始梅萨队列）的遗传分析也表明，整个梅萨队列需要全基因组策略。 2009年为这项活动提供了资金。 有关梅萨研究及其辅助项目（如梅萨Family）的更多信息，包括合作者和参与机构的列表，请参见http://www.mesa-nhlbi.org。

Recruitment of African American and Hispanic sibships for MESA Family began in May 2004. By the end of 2006, when enrolled was complete, 3026 shipships from 608 families were enrolled. On this MESA Family sample, phenotype annotation and genotyping of candidate genes has been completed. Preliminary results from candidate genes analyses indicated that further genotyping would be required before, and this activity has been on-going. Genetic analyses on a subsample of MESA index cases (from the original MESA cohort) also indicated that genome-wide strategies would be required on the entire MESA cohort. Funding for this activity was provided in 2009. For additional information about the MESA study and projects ancillary to it such as MESA Family, including a list of collaborators and participating institutions, see http://www.mesa-nhlbi.org.