Multi-ethnic Study Of Atherosclerosis - Vision Component

动脉粥样硬化的多种族研究 - 视觉成分

• 批准号: 7968338
• 负责人: Mary Frances Cotch
• 金额: $ 12.25万
• 依托单位: NATIONAL EYE INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7968338
• 关键词: African American; Air Pollution; Ancillary Study; Asian Americans; Atherosclerosis; Biological; Cardiovascular Diseases; Caucasians; Caucasoid Race; Cohort Studies; Contracts; Data Analyses; Diabetic Angiopathies; Diabetic Retinopathy; Ethnic Origin; Eye; Funding; Fundus photography; Future; Hispanics; Institution; Laboratories; Lung; Macular degeneration; Manuscripts; Measures; National Heart, Lung, and Blood Institute; Paper; Pathology; Phase; Phenotype; Predictive Factor; Preparation; Process; Protocols documentation; Publications; Publishing; Research Personnel; Retinal; Sampling; Severities; Systemic disease; Vision; Visit; Visual; Visual Acuity; Visual impairment; Woman; Work; aged; cohort; design; digital; follow-up; genome-wide; imaging modality; men; population based; sex

This project remains in an intense data analysis phase. Analyses of various ocular phenotypes, including retinal microvascular disease, have resulted in multiple published manuscripts with more in press, or are under preparation. Results from genome-wide analyses are just beginning to become available and will be a focus of future efforts. Plans to re-examine this cohort in 2010 (visit 5) have been developed, reviewed, and funded. Study protocols and other preparatory work to implement this follow-up examination have been on-going. The MESA Study has several ancillary studies one of which is this ocular component. Others ancillary studies to MESA include a lung component (funded by NHLBI) and an air pollution component (funded by the EPA). Discussions to integrate and analyze data across various study components have resulted in several paper proposals with manuscripts in process. More information about the MESA Study, including a full list of participating investigators and institutions and a complete list of publications to-date, can be found at http://www.mesa-nhlbi.org.

该项目仍处于密集的数据分析阶段。 对各种眼部表型（包括视网膜微血管疾病）的分析已导致多篇已发表的手稿，更多的手稿正在出版或正在准备中。全基因组分析的结果刚刚开始提供，并将成为未来工作的重点。 2010年重新检查这一组的计划（第5次访问）已经制定、审查和供资。 为进行这项跟进研究而制订的研究程序和其他筹备工作，一直在进行中。 梅萨研究有几项辅助研究，其中一项是眼部部分。 梅萨的其他辅助研究包括肺部部分（由NHLBI资助）和空气污染部分（由EPA资助）。 整合和分析不同研究组成部分的数据的讨论已经产生了几份论文提案，手稿正在进行中。 有关梅萨研究的更多信息，包括参与研究者和机构的完整列表以及迄今为止出版物的完整列表，可以在http://www.mesa-nhlbi.org上找到。