New Insights into the Biology of Exercise

摘要 请求支持题为《运动生物学的新见解》的Keystone研讨会， 由Sue Bodine博士、Bret H.Goodpaster和John P.Thyfat博士组织。会议将在#年举行 科罗拉多州Keystone，2019年3月1日至5日。 人们普遍认为，锻炼和有规律的体力活动对保持整体健康和 身体健康。此外，运动已被证明是一种有效的预防和治疗方法 包括糖尿病、肥胖症、心血管疾病和癌症在内的各种疾病。生理学 选定的组织，如骨骼肌、心脏、肝脏、脂肪和大脑对运动的反应 在健康和不健康的个体中进行了不同程度的研究；然而，细胞和分子 运动的急性反应和训练适应的潜在机制仍然不清楚。这个 对运动的研究并不是一个新领域，但由于许多促进健康的研究而受到越来越多的关注 定期进行有氧运动和阻力运动的好处。本次会议包括精选的演讲者，他们可以 提出了与多种器官/组织(骨骼肌、肝脏、脂肪组织、 心脏、血管、大脑)在动物模型和人类中进行锻炼。的首要目标是 会议的目的是1)鼓励对运动的综合多器官反应的讨论，2)鼓励 基础研究和翻译研究的讨论和整合，以及3)为调查人员提供环境 建立网络并发起新的协作。

ABSTRACT Support is requested for a Keystone Symposia conference entitled New Insights into the Biology of Exercise, organized by Drs. Sue Bodine, Bret H. Goodpaster and John P. Thyfault. The conference will be held in Keystone, Colorado from March 1-5, 2019. Exercise and regular physical activity are widely recognized to be important for maintaining overall health and wellness. Furthermore, exercise has been proven to be an effective therapy for the prevention and treatment of a variety of diseases including diabetes, obesity, cardiovascular disease, and cancer. The physiological response of selected tissues, such as skeletal muscle, heart, liver, adipose, and brain to exercise has been studied to varying degrees in healthy and unhealthy individuals; however, the cellular and molecular mechanisms underlying the acute responses and training adaptations to exercise remain poorly defined. The study of exercise is not a new field but is receiving increased interest because of the many health-promoting benefits of regular aerobic and resistance exercise. This conference includes selected speakers who can present new findings related to the response of multiple organs/tissues (skeletal muscle, liver, adipose tissue, heart, vascular, brain) to exercise in both animal models and humans. The overarching goals for the conference are to 1) encourage discussion of the integrative multiple organ response to exercise, 2) encourage discussion and integration of basic and translational research, and 3) provide an environment for investigators to network and initiate new collaborations.