New Hampshire IDeA Network of Biomedical Research Excellence (NH-INBRE)

 描述(由申请人提供)：本申请旨在续期支持新汉普郡IDEA生物研究卓越网络(NH-INBRE)的拨款，建议1)继续改善合作伙伴的生物医学研究基础设施；2)继续增加该州本科生的研究机会；3)继续在合作伙伴建设在第一期支持期间创建的科学和研究文化；4)继续加强NH工作人员的科学和技术培训；以及5)继续加强现代生物医学研究所需的生物信息学和基因组学基础设施。该网络的组成和组织情况说明了其头4年所取得的进展，拟议的牵头机构将继续是达特茅斯的盖泽尔医学院，该学院将是NH-INBRE行政核心的所在地。达勒姆的新汉普郡大学将继续作为联合牵头机构。拟议的伙伴机构包括6个四年制机构，主要是本科生机构和新汉普郡的社区学院系统。NH-INBRE的主题将是微生物致病、细胞和分子生物学、神经生物学和行为学以及人类健康。NH-INBRE将继续由一个由有成就的教师组成的团队领导，他们都是活跃的、由联邦资助的研究实验室的负责人。该小组是NH-INBRE的行政核心(AC)，将由首席调查员罗纳德·K·泰勒博士领导。与将整个行政职能交到首席调查员和项目协调员手中不同，这一团队概念在建立NH-INBRE和启动各种计划方面证明是非常有效的。该团队将继续作为一个整体发挥作用。NH-INBRE的不同组成部分(CORES和发展研究项目计划)将通力合作，实现NH-INBRE的目标，并评估所有NH-INBRE计划。将继续利用各种指标对NH-INBRE进行持续评估和改进。NH-INBRE计划是围绕以下相关理念组织的，即原创科学研究是大学生科学培训的重要组成部分，扩大我们提议的合作机构的学生和教职员工在其校园内参与原创科学研究对于在新罕布什尔州的高等教育机构和整个州内灌输生物医学研究文化至关重要。

 DESCRIPTION (provided by applicant): This application for renewal of the grant supporting the New Hampshire IDeA Network of Biological Research Excellence (NH-INBRE) proposes to 1) Continue to improve the biomedical research infrastructure at the Partners; 2) Continue to increase research opportunities for undergraduates in the state; 3) Continue to build the science and research culture at the Partners that was created during the first period of support; 4) Continue to enhance the science and technology training of the NH workforce; and 5) Continue to enhance the bioinformatics and genomics infrastructure that is required for modern biomedical research. The components and organization of the Network are described as is the progress made during its first 4 years The proposed Lead institution will continue to be the Geisel School of Medicine at Dartmouth, which will house the NH-INBRE Administrative Core. The University of New Hampshire at Durham will continue to be the co- Lead institution. The proposed Partner institutions include 6 four-year primarily undergraduate institutions and the Community College System of New Hampshire. The themes of the NH-INBRE will be Microbial Pathogenesis, Cellular and Molecular Biology, Neurobiology and Behavior, and Human Health. NH-INBRE will continue to be directed by a team of accomplished faculty, all of whom direct active, federally-funded research laboratories themselves. This team constitutes the Administrative Core (AC) of NH-INBRE and will be led by Principal Investigator Dr. Ronald K. Taylor. This team concept, as opposed to placing the entire administrative functions in the hands of only the Principal Investigator and Program Coordinator, has proven very effective in establishing NH-INBRE and initiating diverse programs. The team will continue to function as a unit. Different components of NH-INBRE (Cores and the Developmental Research Projects Program) will work collaboratively accomplish the goals of NH-INBRE and to evaluate all NH-INBRE programs. A wide variety of metrics will continue to be utilized for ongoing evaluation and improvement of the NH-INBRE. The NH-INBRE plan is organized around the related ideas that original scientific research is a vital part of scientific training for college students, and expanding the participation of students and faculty at our proposed Partner institutions in original scientific research on their campuses is essential for instilling a culture of biomedical research within New Hampshire's institutions of higher education and the state overall.