Biotechnology Training Program

生物技术培训计划

• 批准号: 10650330
• 负责人: BRIAN G FOX
• 金额: $ 106.11万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10650330
• 关键词: Biotechnology; Training Programs

PROJECT SUMMARY/ABSTRACT This proposal requests establishment of a new NIGMS T32 Biotechnology Training Program at UW-Madison. BTP has an aim of increasing mentoring skills through provision of WISCIENCE- and NRMN-inspired workshops to our mentors deepen skills and impacts in the promotion of excellence in science. For our trainees, our aim is to improve their ability to clearly communicate the basics of science and also to understand the constraints and solutions to carrying out rigorous, reproducible and responsible research across the breadth of topics relevant to a successful career in biotechnology. Our training plan focuses on supporting a diversity of trainees and helping them to learn to speak clearly and interact effectively with a breadth of colleagues. This is the basis for our cross-disciplinary career development efforts. Each year, BTP receives up to 100 applications from new TGE students that join our mentor’s labs. This high level of interest reflects the visible, innovative and successful training that BTP provides at UW-Madison. BTP requests support for 11 new trainees each year from this large group of enthusiastic applicants and continued support for a 2nd year, accounting for our request for a total of 22 NIGMS-funded trainees each year. BTP trainees will receive NIGMS support during the 2nd and 3rd years of graduate school and participate in BTP program activities during all years they are in graduate school. BTP trainees (with mentor guidance) will have leading roles in organizing, teaching and presenting in a completely revamped BTP Seminar, which provides the framework for our cross-disciplinary approach to integrative training in rigorous, reproducible and responsible conduct of research. Trainees also complete courses in responsible conduct of research in the 1st and 4th years, a required course in rigorous and reproducible methods of research, and an innovative class in entrepreneurship that sets the stage for internships. BTP trainees will complete internships and other career advancement opportunities through a newly formed innovative connection to the biotechnology trade advocacy group BioForward Wisconsin, its ~150 industry members and other sponsors. BTP is committed to tracking and analyzing the outcomes of its programs, trainees, mentors and internship sponsors. We will use professionally designed and distributed anonymous surveys, personal interviews, institutional data and social media to continue this effort and enlist professionals from the UW-Madison Survey Center and LEAD to carry out independent assessment and analysis to continually improve the impacts and outcomes of the BTP.

项目概要/摘要 该提案要求在以下地点建立新的 NIGMS T32 生物技术培训计划： 威斯康星大学麦迪逊分校。 BTP 的目标是通过提供 WISCIENCE 来提高指导技能- 以及 NRMN 启发的研讨会，为我们的导师提供加深技能和影响力，以促进 科学上的卓越表现。对于我们的学员来说，我们的目标是提高他们清晰沟通的能力 科学的基础知识，并了解执行的限制和解决方案 在与某个相关的主题范围内进行严格、可重复和负责任的研究 在生物技术领域取得成功的职业生涯。我们的培训计划侧重于支持多元化 学员，帮助他们学会清晰地说话并与广泛的人有效互动 同事。这是我们跨学科职业发展努力的基础。 每年，BTP 都会收到多达 100 份来自加入我们的 TGE 新学生的申请 导师的实验室。这种高度的兴趣反映了可见的、创新的和成功的培训 BTP 在威斯康辛大学麦迪逊分校提供。 BTP 请求每年为 11 名新学员提供支持 这一大群热情的申请者和第二年的持续支持，占 我们要求每年总共有 22 名 NIGMS 资助的实习生。 BTP 学员将接受 NIGMS 在研究生院第二年和第三年期间提供支持并参与 BTP 计划活动 多年来他们都在读研究生。 BTP 学员（在导师指导下）将有 在彻底改版的 BTP 研讨会中担任组织、教学和演示的主导角色， 它为我们跨学科的综合培训方法提供了框架 严格、可重复且负责任的研究行为。学员还完成以下课程 在第一年和第四年负责任地进行研究，这是严格和严格的必修课 可重复的研究方法，以及一个创新的创业课程，它设定了 实习阶段。 BTP 学员将完成实习和其他职业发展 通过与生物技术贸易新建立的创新联系获得机遇 威斯康星州 BioForward 倡导组织及其约 150 名行业成员和其他赞助商。 BTP 致力于跟踪和分析其项目、学员、导师的成果 和实习赞助商。我们将使用专业设计和分发的匿名 调查、个人访谈、机构数据和社交媒体，以继续这项努力并招募 来自威斯康星大学麦迪逊分校调查中心和 LEAD 的专业人员开展独立的调查 评估和分析，以持续改进 BTP 的影响和成果。

项目成果

Systemic paralogy and function of retinal determination network homologs in arachnids.

• DOI: 10.1186/s12864-020-07149-x
• 发表时间: 2020-11-23
• 期刊: BMC genomics
• 影响因子: 4.4
• 作者: Gainett G;Ballesteros JA;Kanzler CR;Zehms JT;Zern JM;Aharon S;Gavish-Regev E;Sharma PP
• 通讯作者: Sharma PP

Forgotten fungi: the importance of the skin mycobiome.

• DOI: 10.1016/j.mib.2022.102235
• 发表时间: 2022-12
• 期刊: CURRENT OPINION IN MICROBIOLOGY
• 影响因子: 5.4
• 作者: Nguyen, Uyen Thy;Kalan, Lindsay R.
• 通讯作者: Kalan, Lindsay R.

Correlative metabologenomics of 110 fungi reveals metabolite-gene cluster pairs.

• DOI: 10.1038/s41589-023-01276-8
• 发表时间: 2023-07
• 期刊: NATURE CHEMICAL BIOLOGY
• 影响因子: 14.8
• 作者: Caesar, Lindsay K. K.;Butun, Fatma A. A.;Robey, Matthew T. T.;Ayon, Navid J. J.;Gupta, Raveena;Dainko, David;Bok, Jin Woo;Nickles, Grant;Stankey, Robert J. J.;Johnson, Don;Mead, David;Cank, Kristof B. B.;Earp, Cody E. E.;Raja, Huzefa A. A.;Oberlies, Nicholas H. H.;Keller, Nancy P. P.;Kelleher, Neil L. L.
• 通讯作者: Kelleher, Neil L. L.

Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction.

• DOI: 10.1039/d0lc00546k
• 发表时间: 2020-10-21
• 期刊: Lab on a chip
• 影响因子: 6.1
• 作者: Qian T;Gil DA;Contreras Guzman E;Gastfriend BD;Tweed KE;Palecek SP;Skala MC
• 通讯作者: Skala MC

Rapid and precise tracking of water influx and efflux across cell membranes induced by a pulsed electric field.

快速、精确地跟踪脉冲电场诱导的水在细胞膜上的流入和流出。

• DOI: 10.1364/boe.485627
• 发表时间: 2023
• 期刊: Biomedical optics express
• 影响因子: 3.4
• 作者: Steelman,ZacharyA;Martens,Stacey;Tran,Jennifer;Coker,ZacharyN;Sedelnikova,Anna;Kiester,AllenS;O'Connor,SeanP;Ibey,BennettL;Bixler,JoelN
• 通讯作者: Bixler,JoelN