Metabolic wiring in adipocytes - unique role in maintaining long-term health
Metabolic wiring in adipocytes - unique role in maintaining long-term health
批准号:
nhmrc : GNT1086850
负责人:
Prof David James
金额:
$103.62万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 --
中文摘要
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英文摘要
Fat cell metabolism is wired to optimize the cell’s ability to make and store lipid while programming the cell to fulfil its function in whole body metabolism. We will: 1) map fat cell metabolism under optimal and insulin resistant conditions; 2) explore the role of 3 nodes in his metabolic circuit predicted as control points; 3) use a novel genetically engineered mouse model to explore the functional significance of fat cell metabolism in whole body insulin sensitivity.
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财政年份:2017
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Metabolic wiring in adipocytes - unique role in maintaining long-term health
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Dissecting The Role of Selective Insulin Resistance In Type 2 Diabetes
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依托单位:
Research Fellowship
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项目类别:Research Fellowships
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财政年份:2012
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Pathways to Diabetes Prevention
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资助金额:$746.85万
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财政年份:2009
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负责人:Prof David James
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Regulation of Energy Expenditure
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批准号:nhmrc : 481330
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资助金额:$17.73万
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财政年份:2008
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负责人:Prof David James
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Deciphering the molecular basis of SM regulation of exocytosis
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批准号:nhmrc : 401643
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财政年份:2007
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Research Fellowship - Grant ID:427600
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项目类别:NHMRC Research Fellowships
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资助金额:$51.07万
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财政年份:2007
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依托单位:
Dissection of Insulin Regulated Phosphorylation in the Adipocyte
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依托单位:
The Role of AS160 in Insulin Action
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资助金额:$33.71万
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财政年份:2006
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负责人:Prof David James
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依托单位:
Mechanistic studies of c-Cbl - a modulator of energy homeostasis.
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批准号:nhmrc : 325624
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项目类别:NHMRC Project Grants
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资助金额:$30.31万
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Regulation of glucose homeostasis and insulin signalling by Grb10 and Grb14.
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批准号:nhmrc : 325614
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资助金额:$32.31万
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Uncoupled Research Fellowship
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项目类别:NHMRC Research Fellowships
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资助金额:$46.01万
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财政年份:2002
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负责人:Prof David James
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依托单位:
Ongoing uncoupled research fellowship
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批准号:nhmrc : 143142
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项目类别:NHMRC Research Fellowships
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财政年份:2001
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Molecular regulation of GLUT4 trafficking
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负责人:Prof David James
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依托单位:
海外基金