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Metabolic wiring in adipocytes - unique role in maintaining long-term health

Metabolic wiring in adipocytes - unique role in maintaining long-term health
脂肪细胞的代谢线路——在维持长期健康方面的独特作用
批准号:
nhmrc : 1086850
负责人:
Prof David James
金额:
$71.87万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31

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中文摘要
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英文摘要
Fat cell metabolism is wired to optimize the cell’s ability to make and store lipid while programming the cell to fulfil its function in whole body metabolism. We will: 1) map fat cell metabolism under optimal and insulin resistant conditions; 2) explore the role of 3 nodes in his metabolic circuit predicted as control points; 3) use a novel genetically engineered mouse model to explore the functional significance of fat cell metabolism in whole body insulin sensitivity.
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Unravelling a canonical mitochondrial stress response pathway
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    DP210102099
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $38.36万
  • 财政年份:
    2021
  • 负责人:
    Prof David James
  • 依托单位:
Mapping the genetic and lifestyle landscape of Healthy Ageing
  • 批准号:
    FL200100096
  • 项目类别:
    Australian Laureate Fellowships
  • 资助金额:
    $239.5万
  • 财政年份:
    2021
  • 负责人:
    Prof David James
  • 依托单位:
Integrated Multimodal System for Multiplexed Imaging of Signal Transduction
  • 批准号:
    LE210100011
  • 项目类别:
    Linkage Infrastructure, Equipment and Facilities
  • 资助金额:
    $60.01万
  • 财政年份:
    2021
  • 负责人:
    Prof David James
  • 依托单位:
Novel regulatory mechanisms for the protein kinase Akt
  • 批准号:
    DP180103482
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $37.13万
  • 财政年份:
    2018
  • 负责人:
    Prof David James
  • 依托单位:
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