A Wireless CMOS Device for Rapid Point-of-Care Diagnosis of Bacterial Infections and Antibiotic Susceptibility Profiling
A Wireless CMOS Device for Rapid Point-of-Care Diagnosis of Bacterial Infections and Antibiotic Susceptibility Profiling
批准号:
462274-2014
负责人:
Gulak, Glenn
金额:
$17.44万
依托单位:
依托单位国家:
加拿大
项目类别:
Collaborative Health Research Projects
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31
中文摘要
加拿大传染病基金会估计,25%的就诊医生与传染病有关
并导致每年总计120亿英镑的治疗费用和生产力损失。我们已经开发出一种一次性的
一种微芯片,能够在不到10分钟的时间内识别和键入活细菌,而不需要细菌培养步骤。
这项技术将感染和杀死细菌的病毒(噬菌体)的特异性与
电子电路创造了一种低成本、便携式的检测系统。该系统还可用于快速抗生素
药敏分析将提供积极的抗生素管理。
英文摘要
The Canadian Foundation for Infectious Diseases estimates that 25% of all physician visits are related to infectious diseases
and result in a total cost of >$12billion annually for treatment and lost productivity. We have developed a disposable
microchip that is able to identify and type live bacteria in less than ten minutes with no bacterial culturing steps required.
This technology combines the specificity of viruses (phages) that infect and kill bacteria with the sensitivity of integrated
electronic circuits to create a low-cost, portable detection system. The system can also be used to allow rapid antibiotic
susceptibility profiling that would provide positive antibiotic stewardship.
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