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Detection of disease causing genes of aggressive periodontitis by recessive analysis

Detection of disease causing genes of aggressive periodontitis by recessive analysis
隐性分析检测侵袭性牙周炎致病基因
批准号:
23659978
负责人:
KURIHARA Hidemi
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012

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中文摘要
翻译
本研究应用纯合性作图和外显子组测序技术检测了侵袭性牙周炎患者中ARHGF16、SLC2A7、SLC2A5、CASZ 1四种基因突变。然而,在我们的散发性和对照外显子组中未检测到这些突变。需要更多的样本进行检查
英文摘要
We detected the four mutations (ARHGF16, SLC2A7, SLC2A5, CASZ1) in patients with aggressive periodontitis by using homozygosity mapping and exome sequence. However, these mutations were not detected in our sporadic and control exomes. More samples are needed to be examined
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海外基金