CORE--ANALYTICAL

核心部分的目标有三个：提供中央- 质谱学分析和寡聚脱氧核苷酸设备 综合，以支持一系列研讨会，邀请演讲者讨论 与计划成员进行相关研究，并提供行政管理 对本计划参与者的支持。 质谱学在外环化合物分析中起着至关重要的作用 结构和合成中间体；此外，一个重要的新的 组件，LC/MS热喷雾系统，正被添加到我们目前的质量中 光谱设备。把这方面的研究放在核心位置 设施将确保它可以免费提供给调查人员 程序。寡聚脱氧核苷酸的合成是几个 项目；这可以通过集中的 服务设施。

The objectives of the core component are three-fold: to provide central- ized facilities for mass spectrometric analyses and oligodeoxynucleotide synthesis, to support a seminar series for invited speakers to discuss related research with Program members, and to provide administrative support for participants in this Program. Mass spectrometry plays a critical role in the analysis of exocyclic structures and synthetic intermediates; furthermore, a important new component, the LC/MS thermospray system, is being added to our current mass spectrometry facilities. Placing this aspect of the research in the core facility will ensure that it is freely available to investigators in the Program. Synthesis of oligodeoxynucleotides is essential for several Projects; this can most effectively be accomplished by a centralized service facility.