Chemical Biology and Novel Tools in Pharmacology

描述（由申请人提供）：本提案请求支持由Laura L.作者声明：Kiessling，Kevan M. Shokat和Jason Gestwicki，将于2012年2月12日至16日在新墨西哥州圣达菲举行。生物医学科学中最重要问题的最佳解决方案来自多学科研究。特别是，发现新的化学探针和疗法需要跨领域的专业知识和新技术的创新应用。然而，科学论坛已变得越来越专业化，其范围也越来越窄。化学生物学和药理学新工具会议的具体目的是发起和促进学术和工业研究人员在药理学工具的更广泛领域之间的积极讨论。本次会议将汇集各种专家，而不是专注于特定的疾病，模型系统或技术方法，他们的主要共同特点是创新地使用化学和生物学方法来解决生物学中的重要问题。根据这一组织原则，本次会议的具体目标如下：（a）聚集通常可能不会相互交流的化学家和生物学家，（B）在化学家和生物学家、学术界和工业科学家之间建立新的联系，（c）为现代、跨平台思想的公开讨论提供一个论坛。越来越专业化的科学讨论论坛的一个意外后果是缺乏传播新思想、平台和方法的机制。本次会议的主要创新之处在于，它旨在鼓励和激励研究人员探索和实施化学生物学和药理学中的跨学科和新兴方法，以解决他们的特定生物学问题。 公共卫生相关性：越来越专业化的科学讨论论坛抑制了新思想、平台和方法的传播。相比之下，化学生物学和药理学新工具的基石研讨会旨在鼓励和激励研究人员探索和实施化学生物学和药理学中的跨学科和新兴方法，以解决他们特定的生物学问题。我们预计，化学家与生物学家在多个子学科以及学术界和工业界的整合，将加速化学探针向人类治疗的转化。

DESCRIPTION (provided by applicant): This proposal requests support for a Keystone Symposia meeting entitled Chemical Biology and Novel Tools in Pharmacology, organized by Laura L. Kiessling, Kevan M. Shokat and Jason Gestwicki, which will be held in Santa Fe, New Mexico from February 12 - 16, 2012. The best solutions to the most important problems in biomedical science have come from multi-disciplinary research. In particular, the discovery of new chemical probes and therapeutics requires cross-cutting expertise and the innovative application of new technologies. Scientific forums, however, have become increasingly specialized and narrow in their scope. The specific purpose of the Keystone Symposia meeting on Chemical Biology and Novel Tools in Pharmacology is to initiate and foster active discussions between academic and industrial researchers in the broader area of pharmacological tools. Rather than focus on a specific disease, model system, or technical method, this meeting will bring together a variety of experts whose primary, common trait is their innovative use of chemical and biological approaches to solve important problems in biology. From this organizing principle, the specific aims of this meeting have been devised as follows: (a) to assemble chemists and biologists who may not normally interact with each other, (b) to make new connections between chemists and biologists, academics and industrial scientists and (c) to provide a forum for an open discourse of modern, cross-platform ideas. An unintended consequence of increasingly specialized forums for scientific discussions is the lack of mechanisms for dissemination of novel ideas, platforms, and methodologies. The major innovation of this meeting is that it is designed to encourage and inspire researchers to explore and implement inter-disciplinary and emerging methods in chemical biology and pharmacology to their specific biological questions. PUBLIC HEALTH RELEVANCE: Increasingly specialized forums for scientific discussions inhibit dissemination of novel ideas, platforms and methodologies. In contrast, the Keystone Symposia meeting on Chemical Biology and Novel Tools in Pharmacology is designed to encourage and inspire researchers to explore and implement inter-disciplinary and emerging methods in chemical biology and pharmacology to their specific biological question. We expect that the integration of chemists with biologists, across multiple sub-disciplines and in both academics and industry, will accelerate translation of chemical probes into human therapeutics.