NATIONAL NEUROLOGICAL AIDS BANK

项目总结/摘要 有必要对人脑组织进行研究，以了解艾滋病毒和共病状况的影响 例如中枢神经系统的阿片类药物使用障碍。自1998年以来，国家神经艾滋病银行（NNAB） 从一组HIV血清阳性（HIV+）参与者中收集脑组织和数据。这样做的目的 行政补充是继续NNAB正在进行的工作后，我们的无成本时间延长资金是 预计将用完（估计2023年6月1日），并在合同审查和谈判之前（估计 2023年8月下旬这些资金将用于支付研究者/工作人员的工资、用品、组织费用等费用 采集、处理、储存和运送组织给经批准的研究人员。我们的样本和数据可以 在合同获得批准之前，调查人员可以通过我们的分配流程继续使用这些资源。

Project Summary/Abstract There is a need for human brain tissues in research to understand the impact HIV and co-morbid conditions such as opioid use disorders on the CNS. Since 1998, the National Neurological AIDS Bank (NNAB) has collected brain tissues and data from a cohort of HIV-seropositive (HIV+) participants. The purpose of this administrative supplement is to continue the ongoing work of NNAB after our no-cost time extension funds are expected to run out (estimated June 1, 2023) and before the contract is reviewed and negotiated (estimated late August, 2023. The funds will pay such costs as salary of investigators/staff, supplies, costs of tissue acquisition, processing, storage, and to ship tissue to approved researchers. Our samples and data can then continue to be available to investigators through our allocations process until the contracts are approved.