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Natural history, pathogenesis, and treatment of alopecia

Natural history, pathogenesis, and treatment of alopecia
脱发的自然史、发病机制和治疗
批准号：
10925945
负责人：
Heidi Kong
金额：
$21.32万
依托单位：
NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10925945
关键词：
AdultAlopeciaBiologicalCharacteristicsChildhoodClinicalEtiologyGene ExpressionGeneticGoalsHairImmuneImmunologicsImmunologyIndividualInterruptionMediatingNatural HistoryPathogenesisPatientsProductionSkinSystemic diseaseTreatment outcomeclinical phenotypecohortimprovedinterestmicrobiometreatment response

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中文摘要
翻译
该项目的目标是系统地评估脱发(脱发)患者的队列，以研究特定类型脱发的自然病史。我们将使用临床和翻译(基因表达、免疫学、微生物组和遗传学)方法来扩大我们对脱发的发病机制和导致不同临床表型的因素的理解。此外，我们将研究患者在接受脱发治疗时的情况，以了解治疗反应。最终目标将是改善脱发患者的治疗结果。
英文摘要
The goal of this project is to systematically evaluate cohorts of alopecia (hair loss) patients to study the natural history of defined forms of alopecia. We will use clinical and translational (gene expression, immunology, microbiome, and genetics) approaches to expand our understanding of the pathogenesis of alopecia and the factors that contribute to the different clinical phenotypes. Additionally, we will study patients as they undergo treatment of alopecia to understand therapeutic responses. The ultimate goal will be to improve treatment outcomes for alopecia patients.
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