Glycoscience Training Program

描述(申请人提供)：复合碳水化合物或多聚糖是生命的四大分子之一，与核酸、蛋白质和脂类一起。这些生物分子基本上参与了所有的生理或病理过程。最近，美国国家科学院国家研究理事会审查了糖科学的重要性和机遇，由此产生的题为《改造糖科学：未来路线图》的报告强调了教育对促进这一研究领域的重要性。我们在这项申请中提出了一个新的在化学和生物学接口的糖科学研究生培训计划，以开始解决这一日益重要的研究领域中研究生教育的明显不足。由于佐治亚大学在血糖科学方面的专业知识和凝聚力强的研究和教育项目，我们相信乔治亚大学的教职员工是唯一有资格开发这种研究生培训项目的机构。尽管UGA在血糖科学方面有着长期的记录，但在这一领域还没有正式的研究生培训计划。在过去的四年里，私人考辛斯基金会为两到四名即将入学的研究生提供了两年的血糖科学支持；然而，它已经不再存在了。该计划作为T32血糖科学培训计划(GTP)应用的“试点”计划，支持CHEM和BCMB研究生。建议的T32计划将允许我们开发化学/生物学接口程序，并提供糖科学博士前培训的蓝图。血糖科学培训计划(GTP)的17名培训教员在生物化学、分子生物学和化学系设有初级和二级职位，这些系是富兰克林艺术与科学学院的一部分。该计划的使命是通过整合化学和生物方法，严格和广泛地培训糖科学方面的博士前学生。此外，还将侧重于招收来自代表性不足的少数族裔的学生，进行生物伦理培训，并发展学生优秀的写作和沟通技能。

DESCRIPTION (provided by applicant): Complex carbohydrates or glycans are one of the four classes of macromolecules of life along with nucleic acids, proteins, and lipids. These biomolecules are involved in essentially all physiological or pathological processes. Recently, the National Research Council of The National Academies reviewed the importance and opportunities of Glycoscience, and the resulting report entitled "Transforming Glycoscience: A Road Map for the Future" highlights the importance of education to further this field of research. We propose in this application a new graduate training program in Glycoscience at the Chemistry and Biology interface to begin to address the noted deficiency in graduate education in this increasingly important field of research. Because of its considerable demonstrated expertise and cohesive research and educational programs in Glycoscience, we believe the faculty of the University of Georgia is uniquely qualified to develop such a graduate training program. Although UGA has a long-standing track-record in Glycoscience, no formal graduate training program in this area has been in place. Over the past four years, the private Cousins Foundation supported two to four incoming graduate students in Glycoscience for two years; it is however, no longer in place. This program has functioned as a "pilot" program for the T32 Glycoscience Training Program (GTP) application, supporting CHEM and BCMB graduate students. The proposed T32 program will allow us to develop a Chemistry/Biology interface program and provide a blueprint of predoctoral training in Glycoscience. The 17 training faculty of the Glycoscience Training Program (GTP) has primary and secondary appointments in the Biochemistry and Molecular Biology and Chemistry departments, which are part of the Franklin College of Arts and Sciences. The mission of the program is to train predoctoral students rigorously and broadly in Glycoscience by integrating both chemical and biological approaches. In addition, emphasis will be placed on recruiting students from under-represented minorities, bioethics training, and developing students' excellent writing and communication skills.