Frontiers of NMR in Molecular Biology X Scientific Conference

核磁共振在分子生物学领域的前沿 X 科学会议

• 批准号: 7160619
• 负责人: ANDREW D ROBERTSON
• 金额: $ 0.5万
• 依托单位: KEYSTONE SYMPOSIA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-08 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7160619
• 关键词: Affect; Binding; Biological; Catalysis; Chemistry; Development; Disease; Drug Design; Goals; Ligands; Membrane Proteins; Methods; Molecular; Molecular Biology; Molecular Structure; NMR Spectroscopy; Nuclear Magnetic Resonance; Nucleic Acid Folding; Pathway interactions; Physics; Proteins; RNA-Binding Proteins; Range; Recording of previous events; Scientist; Screening procedure; Solutions; Specialist; Structure; System; Techniques; computerized data processing; drug development; frontier; macromolecule; method development; protein folding; protein misfolding; protein structure; solid state; structural biology; symposium

DESCRIPTION (provided by applicant): Frontiers of NMR in Molecular Biology has evolved to be the premier meeting in macromolecular NMR. It brings together leaders in the field in methods development, data processing and analysis, and structural biology using solution and solid state NMR. This meeting will reflect the development and unique applications of NMR spectroscopy for studying biologically important macromolecules and their interactions. This includes analysis of structures along the pathway from free to bound, conformational dynamics that affect catalysis, function, and folding, screening of protein and RNA binding ligands for drug development, studies of misfolded proteins that can cause disease, nucleic acid folding and function, and methods for determining membrane protein structure and activity.

描述（由申请人提供）：分子生物学NMR前沿已发展成为大分子NMR的首要会议。它汇集了方法开发，数据处理和分析以及使用溶液和固态NMR的结构生物学领域的领导者。本次会议将反映核磁共振波谱学的发展和独特的应用研究生物重要的大分子及其相互作用。这包括分析结构沿着的途径从自由到结合，构象动力学影响催化，功能和折叠，筛选蛋白质和RNA结合配体的药物开发，错误折叠的蛋白质，可以导致疾病，核酸折叠和功能的研究，以及用于确定膜蛋白质结构和活性的方法。