UC Irvine Multidisciplinary Exercise Sciences Training Program

加州大学欧文分校多学科运动科学培训计划

• 批准号: 7440795
• 负责人: VINCENT James CAIOZZO
• 金额: $ 15.81万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7440795
• 关键词: Exercise; Science; Training Programs; multidisciplinary

DESCRIPTION (provided by applicant): There continues to be growing recognition that exercise and inactivity can play important roles in many disease processes. The goal of this training grant proposal is to establish a strong and rich research training environment for those M.D.s and Ph.D.s interested in exercise science. The underlying programmatic theme of this training program is that of "integrative/translational" science. Within this context, the prgoram consists of two core groups: the Molecular Physiology Core Group and the Systems Physiology Core Group. The emphasis of these cores is in skeletal muscle, cardiovascular, and respiratory physiology given that these areas of research represent the focus of the Program Faculty, and represent areas of extensive on-going interactions. An integrated/translational approach is especially important in exercise science because of the profound role that physical activity is now known to play in human health. Postdoctoral fellows will interact with the faculty and other trainees through a formal didactic program, seminars, journal clubs, and research-in-progress discussions. At the beginning of the program each fellow will work with the Executive Committee to select a primary and secondary research emphasis designed to reflect an appropriate diversity of topics in exercise science. These emphases will be selected from the two cores. Trainees will become familiar with a variety of animal and cell model systems and state-of-the-art approaches to human performance testing, thereby facilitating the translation from these systems to human research and, ultimately to clinical applications. For this latter objective, Human Performance Laboratory at the U.C. Irvine GCRC/CTSC will play an important role as it is funded specifically to support translational research in an environment that optimizes the safety and quality of human investigation. The Program Faculty have a history of collaborative research with each other and are currently involved in training postdoctoral research fellows. This proposed training program is designed to introduce postdoctoral trainees to new disciplines as they continue to hone skills and approaches mastered in the predoctoral years. For postdoctoral MD.s, the program will attract individuals seriously interested in becoming independent investigators. Exercise physiology is not a separate ACGME-recognized specialty or subspecialty; consequently, MDs pursuing postdoctoral training in this program must be committed to academic careers. For Ph.D.s, the program will be best suited for basic scientists who see their academic careers involving clinical interaction either through direct human research or as members of faculties of medical schools where translational research activity is likely to be encouraged.

描述(由申请者提供)：越来越多的人认识到，锻炼和不活动在许多疾病过程中可以发挥重要作用。这项培训拨款提案的目的是为那些对运动科学感兴趣的医学博士和博士建立一个强大而丰富的研究培训环境。这一培训方案的基本方案主题是“综合/翻译”科学。在这一背景下，PROGORAM由两个核心小组组成：分子生理学核心小组和系统生理学核心小组。这些核心的重点是骨骼肌、心血管和呼吸生理学，因为这些领域代表了计划学院的重点，并代表了广泛正在进行的互动领域。综合/转换方法在运动科学中尤其重要，因为体育活动现在已知在人类健康中发挥着深远的作用。博士后研究员将通过正式的教学计划、研讨会、期刊俱乐部和正在进行的研究讨论与教师和其他实习生互动。在计划开始时，每个研究员将与执行委员会合作，选择主要和次要的研究重点，以反映运动科学中适当多样化的主题。这些重点将从两个核心中挑选出来。学员将熟悉各种动物和细胞模型系统以及最先进的人体性能测试方法，从而促进从这些系统到人体研究的转换，并最终应用于临床。对于后一个目标，加州大学欧文分校GCRC/CTSC的人类行为实验室将发挥重要作用，因为它的资金专门用于支持环境中的翻译研究，以优化人类调查的安全性和质量。该计划学院有相互合作研究的历史，目前参与了博士后研究员的培训。这一拟议的培训计划旨在向博士后学员介绍新的学科，因为他们继续磨练在博士前几年掌握的技能和方法。对于博士后，该项目将吸引对成为独立调查人员感兴趣的个人。运动生理学不是一个单独的ACGME认可的专业或子专业；因此，在这个项目中进行博士后培训的MD必须致力于学术事业。对于博士，该项目将最适合基础科学家，他们认为自己的学术生涯涉及临床互动，要么是通过直接的人体研究，要么是作为医学院的教员，那里的翻译研究活动可能得到鼓励。