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Estrogenicity Of Soy Formula

Estrogenicity Of Soy Formula
大豆配方奶粉的雌激素作用
批准号：
9143419
负责人：
WALTER ROGAN
金额：
$43.26万
依托单位：
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/9143419
关键词：
BreastData AnalysesEstradiolEstrogensGenisteinGonadal Steroid HormonesGonadotropinsGrowth and Development functionInfantIsoflavonesLongitudinal StudiesMethodsModelingOrganOvaryReportingSerumSoybeansTissuesUrethraUterusVaginaValidationdaidzeinfeedingfollow-upsoy

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中文摘要
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英文摘要
Genistein and daidzein are estrogenic isoflavones found in soybeans. Although they are much less potent than estradiol, infants fed soy formula have serum concentrations that are up to 4 orders of magnitude higher than estradiol. We have been in the field with a longitudinal study of infants up to 9 months old, looking in detail at the growth and development of their estrogen-responsive tissue as well as sex hormones and gonadotropins. We completed follow-up in May, 2014, and have begun data analysis. In addition, we reported this year the validation of a cytological method for asessing estrogen exposure in infants.
期刊论文(6)
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科研奖励(0)
会议论文
Perchlorate exposure and dose estimates in infants.
婴儿高氯酸盐暴露和剂量估计。
DOI： 10.1021/es103160j
发表时间： 2011
期刊： Environmental science & technology
影响因子： 11.4
作者： [Valentín-Blasini,Liza, Blount,BenjaminC, Otero-Santos,Samaret, Cao,Yang, Bernbaum,JudyC, Rogan,WalterJ]
通讯作者： Rogan,WalterJ
Association between maternal serum perfluoroalkyl substances during pregnancy and maternal and cord thyroid hormones: Taiwan maternal and infant cohort study.
DOI： 10.1289/ehp.1306925
发表时间： 2014-05
期刊： Environmental health perspectives
影响因子： 10.4
作者： [Wang Y, Rogan WJ, Chen PC, Lien GW, Chen HY, Tseng YC, Longnecker MP, Wang SL]
通讯作者： Wang SL
Maternal obesity and the risk of infant death in the United States.
DOI： 10.1097/ede.0b013e3181878645
发表时间： 2009-01
期刊： Epidemiology (Cambridge, Mass.)
影响因子： --
作者： [Chen A, Feresu SA, Fernandez C, Rogan WJ]
通讯作者： Rogan WJ
Triclosan and prescription antibiotic exposures and enterolactone production in adults.
DOI： 10.1016/j.envres.2015.06.017
发表时间： 2015-10
期刊： Environmental research
影响因子： 8.3
作者： [Adgent MA, Rogan WJ]
通讯作者： Rogan WJ
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