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An investigation into Infection, Immunity & Rational Drug Design

An investigation into Infection, Immunity & Rational Drug Design
感染、免疫研究
批准号:
FF0668802
负责人:
Prof Jamie Rossjohn
金额:
$110.84万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Federation Fellowships
财政年份:
2006
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2006-12-18 至 2011-12-17

项目摘要

项目成果

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中文摘要
翻译
人类不断受到微生物攻击的威胁。 人类的生存反映了感染和免疫之间的微妙平衡。个体是否产生有效的免疫应答或屈服于微生物感染,关键取决于与微生物抗原有效相互作用的宿主蛋白,而不是微生物发展复杂的入侵和免疫逃避策略。 该提案将为感染和免疫领域的知识提供根本性的进步。 从这项研究中收集的信息将导致治疗学的合理发展。因此,这项研究将有可能在生物医学健康领域产生巨大的全球影响。
英文摘要
The human population is constantly under threat of microbial attack. The survival of our species reflects a delicate balance between infection and immunity. Whether an individual mounts an effective immune response or succumbs to microbial infection is critically dependent on host proteins interacting effectively with microbial antigens, versus microbes developing sophisticated strategies of invasion and immune evasion. This proposal will provide fundamental advancement of knowledge in the areas of infection and immunity. The information gleaned from this research will lead to the rational development of therapeutics. Consequently, the research will potentially have an enormous global impact in the area of biomedical health.
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海外基金