权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Myeloid Cells: Development, Diversity and Distinct Biological Roles

骨髓细胞：发育、多样性和独特的生物学作用

基本信息

批准号：
10609155
负责人：
TERRY L. SHEPPARD
金额：
$ 1.4万
依托单位：
KEYSTONE SYMPOSIA
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-11-01 至 2023-10-31
项目状态：
已结题

项目摘要

ABSTRACT Support is requested for a Keystone Symposia conference entitled Myeloid Cells: Development, Diversity and Distinct Biological Roles, organized by Drs. Gwendalyn Randolph, Minsoo Kim, Roxane Tussiwand, and Muzlifah Haniffa. The conference will be held in Snowbird, Utah from March 16-19, 2023. It is becoming more evident that myeloid cells participate critically in a variety of physiological and pathophysiological processes and that targeting myeloid cells, either at selected stages of their development or as they mature, may be successfully harnessed in the treatment of cancers or infectious disease. The application of rapidly evolving omics technologies are aiding in the quest to increase understanding of myeloid cell diversity and the potential of targeting them therapeutically. However, at the same time, fundamental questions about myeloid cell identity and function remain unknown. This Keystone Symposia conference will address these frontiers as it aims to attract speakers and attendees across the full breadth of the field. The conference program will include key talks intended to focus on the application of new technologies in the field, the advances they bring, best-practice application, and potential complications in analysis. Significant focus will also be given to the role of myeloid cells in cancer and metastasis, including the fast-growing area of how neutrophils aid tumor metastasis. Basic science that covers myeloid cell development and function will be interspersed with talks on the role of myeloid cells in disease states. In the last decades, the number of outstanding scientists in the field has grown tremendously, and this conference will showcase this growth through inclusion of many new dimensions in the field.

抽象的请求支持题为“骨髓细胞：发育、多样性和独特的生物学角色，由博士组织。格温达琳·兰道夫、金民秀、罗克珊·图西旺德和穆兹利法·哈尼法。会议将于2023年3月16日至19日在犹他州斯诺伯德举行。越来越明显的是，骨髓细胞在多种生理和功能中发挥着重要作用。病理生理过程以及针对骨髓细胞的病理生理过程，无论是在其发育的选定阶段还是当它们成熟时，可以成功地用于治疗癌症或传染病。这快速发展的组学技术的应用有助于增进对骨髓的了解细胞多样性以及针对它们进行治疗的潜力。但与此同时，基本面关于骨髓细胞的身份和功能的问题仍然未知。本次 Keystone 研讨会将解决这些前沿问题，因为它的目的是吸引整个领域的演讲者和与会者。这会议计划将包括旨在重点关注新技术在该领域的应用的重要演讲，它们带来的进步、最佳实践应用以及分析中潜在的复杂性。重点突出还将关注骨髓细胞在癌症和转移中的作用，包括快速增长的领域中性粒细胞有助于肿瘤转移。涵盖骨髓细胞发育和功能的基础科学将是穿插了有关骨髓细胞在疾病状态中的作用的讨论。在过去的几十年里，数量该领域的杰出科学家取得了巨大的成长，本次会议将展示这种成长通过纳入该领域的许多新维度。